Tomoh Matsumiya Selected Research

Toll-Like Receptor 3

9/2021	Expression of IFN-induced transmembrane protein 1 in glomerular endothelial cells.
1/2021	Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes.
11/2020	Endothelial expression of fractalkine (CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human glomerular endothelial cells.
1/2020	Toll-Like Receptor 3 as a Recurrence Risk Factor and a Potential Molecular Therapeutic Target in Colorectal Cancer.
1/2018	Gnetin C suppresses double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling pathway.
1/2017	Cylindromatosis (CYLD), a Deubiquitinase, Attenuates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.
1/2017	Interferon (IFN)-induced protein 35 (IFI35) negatively regulates IFN-β-phosphorylated STAT1-RIG-I-CXCL10/CCL5 axis in U373MG astrocytoma cells treated with polyinosinic-polycytidylic acid.
4/2016	Interferon-stimulated gene (ISG) 60, as well as ISG56 and ISG54, positively regulates TLR3/IFN-β/STAT1 axis in U373MG human astrocytoma cells.
5/2015	Desferrioxamine, an iron chelator, inhibits CXCL10 expression induced by polyinosinic-polycytidylic acid in U373MG human astrocytoma cells.
2/2015	Tumor necrosis factor-α synergistically enhances polyinosinic-polycytidylic acid-induced toll-like receptor 3 signaling in cultured normal human mesangial cells: possible involvement in the pathogenesis of lupus nephritis.

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Tomoh Matsumiya Research Topics

Disease

16	Melanoma (Melanoma, Malignant) 02/2022 - 01/2012
12	Virus Diseases (Viral Diseases) 10/2022 - 01/2006
10	Inflammation (Inflammations) 12/2021 - 01/2009
8	Alzheimer Disease (Alzheimer's Disease) 06/2022 - 02/2013
8	Lupus Nephritis 12/2021 - 12/2013
8	Astrocytoma (Pilocytic Astrocytoma) 01/2018 - 06/2007
6	Neuroblastoma 01/2018 - 02/2013
5	Glomerulonephritis 11/2020 - 10/2015
5	Hypoxia (Hypoxemia) 08/2013 - 07/2002
4	Infections 12/2021 - 09/2012
4	Neoplasms (Cancer) 01/2020 - 01/2006
3	Chronic Renal Insufficiency 09/2021 - 01/2017
3	Parkinson Disease (Parkinson's Disease) 01/2018 - 05/2015
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 10/2015
2	Rheumatoid Arthritis 01/2021 - 01/2009
2	Neuroinflammatory Diseases 05/2015 - 07/2014
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2014 - 01/2006
2	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2012 - 02/2011
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2010 - 10/2007
2	Mouth Neoplasms (Oral Cancer) 01/2006 - 05/2004
2	Necrosis 01/2006 - 12/2002
1	Nervous System Diseases (Neurological Disorders) 06/2022
1	Disease Progression 02/2022
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 12/2021
1	Acute Kidney Injury (Acute Renal Failure) 09/2021
1	Aortic Valve Stenosis (Aortic Stenosis) 02/2021
1	Colorectal Neoplasms (Colorectal Cancer) 01/2020
1	Non-alcoholic Fatty Liver Disease 12/2019
1	Purpura 01/2018
1	Nephritis 01/2018
1	Lewy Body Disease (Lewy Body Dementia) 10/2015
1	Dementia (Dementias) 10/2015
1	IGA Glomerulonephritis (IGA Nephropathy) 10/2015
1	Hepatocellular Carcinoma (Hepatoma) 05/2014

Drug/Important Bio-Agent (IBA)

17	Tretinoin (Retinoic Acid)FDA LinkGeneric 02/2022 - 01/2006
11	Proteins (Proteins, Gene)FDA Link 12/2021 - 12/2007
11	Toll-Like Receptor 3IBA 09/2021 - 01/2013
11	Poly I-CIBA 01/2019 - 01/2011
10	Antiviral Agents (Antivirals)IBA 12/2021 - 01/2012
7	InterferonsIBA 01/2018 - 01/2013
7	Interferon Type IIBA 01/2017 - 02/2011
6	CytokinesIBA 12/2019 - 10/2007
5	RNA Helicases (RNA Helicase)IBA 01/2021 - 11/2010
5	ChemokinesIBA 01/2021 - 12/2013
5	Amyloid (Amyloid Fibrils)IBA 01/2018 - 02/2013
5	Amyloid beta-PeptidesIBA 01/2018 - 02/2013
5	Peptides (Polypeptides)IBA 01/2018 - 02/2013
4	Double-Stranded RNA (RNA, Double Stranded)IBA 01/2019 - 06/2007
4	salvinIBA 05/2015 - 04/2011
4	Messenger RNA (mRNA)IBA 01/2014 - 12/2007
3	Chemokine CX3CL1IBA 11/2020 - 12/2002
3	Viral RNAIBA 01/2019 - 12/2012
3	LigandsIBA 01/2018 - 02/2015
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2015 - 10/2007
3	RNA (Ribonucleic Acid)IBA 01/2013 - 01/2008
3	Pattern Recognition ReceptorsIBA 12/2012 - 02/2011
3	EdaravoneIBA 04/2011 - 12/2007
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2007 - 07/2002
3	1-phenyl-3,3-dimethyltriazene (PDT)IBA 07/2007 - 05/2004
2	tryptanthrineIBA 10/2022 - 01/2021
2	Interleukin-6 (Interleukin 6)IBA 06/2022 - 01/2019
2	Chloroquine (Aralen)FDA LinkGeneric 12/2021 - 11/2017
2	ImmunosorbentsIBA 01/2019 - 02/2015
2	EnzymesIBA 01/2019 - 02/2015
2	ResveratrolIBA 01/2018 - 01/2018
2	gnetin CIBA 01/2018 - 01/2018
2	Chemotactic FactorsIBA 01/2018 - 01/2014
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2016 - 10/2015
2	NucleotidesIBA 03/2015 - 02/2011
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 02/2015 - 01/2014
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 02/2014 - 02/2013
2	Nerve Growth Factor (NGF)IBA 04/2011 - 03/2010
2	Photosensitizing Agents (Photosensitizers)IBA 07/2007 - 01/2006
2	Talaporfin (talaporfin sodium)IBA 07/2007 - 01/2006
1	AntigensIBA 02/2022
1	Protein Isoforms (Isoforms)IBA 12/2021
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 12/2021
1	Antimalarials (Antimalarial Agents)IBA 12/2021
1	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 09/2021
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 02/2021
1	Interleukin-8 (Interleukin 8)IBA 01/2020
1	Autophagy-Related ProteinsIBA 01/2018
1	E-SelectinIBA 01/2018
1	rebamipideIBA 11/2017
1	Small Interfering RNA (siRNA)IBA 01/2016
1	SynucleinsIBA 10/2015
1	TrehaloseIBA 10/2015
1	Chelating AgentsIBA 05/2015
1	Deferoxamine (Desferal)FDA LinkGeneric 05/2015
1	IronIBA 05/2015
1	AntioxidantsIBA 03/2015
1	CC ChemokinesIBA 02/2015
1	Serine (L-Serine)FDA Link 05/2014
1	DiterpenesIBA 02/2014
1	mizoribineIBA 01/2014
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2014
1	Interferon-gamma (Interferon, gamma)IBA 01/2014

Therapy/Procedure

3	Therapeutics 03/2010 - 01/2006
2	Photochemotherapy (Photodynamic Therapy) 07/2007 - 01/2006
1	Aftercare (After-Treatment) 01/2018